Because the Nasal Insert uses a flexible line to connect the two insert balls together, the product can instantly adjust to any nose size or shape. The device is not a rigid structure, so the person wearing it does not feel anything hard against the nose or skin. It can thus be comfortably worn under any type of facial mask. Once inserted into the nose, the two pads will remain in place wherever positioned. They do not tend to "wander".
Again, through the use of clear line, the Nasal Insert is simply not visible while being worn. The person using the product remains confident in the presence of others. There is no "visual distraction" to contend with. Also, when one is finished using the insert, he or she can discreetly "blow-the-nose" into tissue paper and discard the device without anyone being aware of its use.
Since the Nasal Insert is small and lightweight, several packaged inserts can easily be carried inside a shirt pocket. When ready to use, the device slips quickly into the nose without complication. When one is through using the product, all one needs to do is "blow-the-nose" into a clean tissue and all scent is instantly removed from the nose.
When used for odor control purposes, the FDA has determined that the UNI is safe enough not to be considered a medical device. In the case of it's potential for delivering medications, the device can naturally be designed to allow for controlled release of a compound with the added ability to stop further flow of that compound by simply removing the insert from the nose. This ability differs from injectables, oral medications and other nasal technologies which are flooded or deposited into the body all at once. If there is a drug or vaccine reaction in the patient these forms of delivery do not offer a way to stop further medication flow into the body. All of the medication is abruptly delivered and must be absorbed.
The UNI could also be a safer delivery technology against abuse and overdosing since generally only one can be used at a time and it would be more difficult to tamper with.
There is normally no pain associated with using the Nasal Insert and it is easily self-administered and thus quite patient friendly.
Each Nasal Insert can be precisely dosed with the exact amount of ingredients to insure quality and effectiveness.
Drug delivery experts have shown that one major way of increasing the absorption of nasally administered drugs is to extend nasal residence time. This is known as the amount of time that the drug or vaccine remains effective inside the nasal cavity. It is well documented that the nose clears itself out approximately every twenty minutes (nasal clearance time), thus removing any foreign substance or irritant within. By acting as a delivery device for various drugs and vaccines the UNI would physically (non-chemically) increase nasal residence time by as much as 8 to 12 hours (overnight). A delivery device with such an ability would strongly increase the possibility of being able to reduce drug dose size. Further, such a device would minimize the need to incorporate additional chemicals to bond the pharmaceutical to the nasal walls as some leading technologies propose.
When compared to conventional syringe technologies a small fraction of the plastic is required to produce and package each UNI. The device would likely require a smaller dose size than conventional technologies which would tend to reduce the overall quantity of a particular drug or vaccine manufacturers would need to produce. When compared to many oral medications which often pass through the body largely undigested, medications delivered by the UNI may be absorbed more efficiently and thoroughly resulting in less of the medication being excreted from the body into toilets and showers. This could help reverse the current hazardous condition of pharmaceuticals entering municipal water supplies. Lastly, the UNI used as a virus filter may prove to be effective at reducing the spread of influenza (and other) viruses worldwide, thus potentially reducing the human, environmental and financial costs associated with these pandemics. All of these advantages would translate into reducing environmental impact and the protection of natural resources.
Demand for nasal drug delivery is expected to increase.
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